IDP Pharma: A New Option for Patients With Difficult-to-Treat Cancer
Frank McGillicuddy
Organizer
Frank McGillicuddy
Organizer
Description
Patients with multiple myeloma and small-cell lung cancer frequently relapse, become resistant to treatment, and eventually exhaust the medicines available to them.
Many of these cancers depend on a protein called cMyc to survive. Despite its importance across cancer, no direct cMyc protein inhibitor has been approved because the protein constantly changes shape and is extremely difficult for conventional drugs to reach.
IDP Pharma’s lead treatment is designed to enter cancer cells and cause them to destroy cMyc. The drug is already being evaluated in a Phase I clinical trial, where company materials report that four dose levels have been tested without dose-limiting toxicities.
Support would directly help move this treatment into Phase II studies in multiple myeloma and small-cell lung cancer, giving researchers the opportunity to directly patients who are running out of options.
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